Seminar Archive

Seminars in 2016

  • Teresa Carlomagno – RNA-protein complexes in RNA metabolism: an integrative structural biology approach (10 Mar, 2016)
  • Philipp Selenko – Looking at proteins in live cells with atomic-resolution: From Science Fiction to Science Reality (24 Mar, 2016)
  • Manuel Etzkorn – Conventional and non-conventional methods for the NMR characterization of (membrane-) protein structure, folding and function (12 Apr, 2016)
  • Björn Burmann – Membrane-protein–chaperone complexes: Elucidating the functional detailsby NMR and AFM (12 Apr, 2016)
  • Hugo van Ingen – Unpinning chromatin: casting shadows of nucleosomes by NMR (22 Apr, 2016)
  • Jana Broecker – Advances in membrane-protein crystallization: From detergent-free crystallization to in situ approaches (22 Apr, 2016)

Seminars in 2015

  • Nicki Packer – Glycomics: the new -omics (13 Mar, 2015)
  • Alan Mark – Activation of cytokine receptors and transport proteins: Turning on micromachines (31 Mar, 2015)
  • Juliane Liepe – Computational models as microscopes: rate-limiting steps in proteasomes (19 May, 2015)
  • Friedrich Förster – Cotranslational protein translocation and membrane insertion in situ (19 May, 2015)
  • Niels de Jonge – Electron microscopy of labeled membrane proteins in whole eukaryotic cells in liquid (20 May, 2015)
  • Chris Abell – Fragment-based approaches in drug discovery and chemical biology (28 Aug, 2015)
  • Katja Petzold – Characterizing Transient Structures of RNA using NMR (10 Sep, 2015)
  • John Briggs – Structure in situ: (cryo-)electron microscopy of viruses and vesicles (1 Oct, 2015)
  • Sandro Keller – Electrostatics trumps hydrophobicity: how to fold a hydrophilic membrane protein (19 Nov, 2015)

Seminars in 2014

  • Daniel Southworth – Architecture and control mechanisms of nitric oxide synthases: essential regulators of mammalian physio (11 Mar, 2014)
  • Henry van den Bedem – Characterizing Biomolecular Ensembles with Molecular-Scale Kinematics (2 Jul, 2014)
  • Remco Sprangers – Detection and analysis of motions in large molecular complexes using novel methods in NMR spectroscopy (22 Sep, 2014)
  • Eduardo Perozo – Structural basis of voltage-dependent gating in ion channels and enzymes (28 Oct, 2014)
  • Yvonne Jones – Norrin and Notum: some new structural insights for the Wnt signalling system (12 Nov, 2014)
  • Kevin H. Mayo – “Galectins: Their Interactions with Polysaccharides and Structure-Based Design of Antagonists for the Clinic (10 Dec, 2014)

Seminars in 2013

  • David Schriemer – Structural Mass Spectrometry of Complex Protein Systems (28 Jan, 2013)
  • Juan Fernández-Recio – Protein-protein docking challenges in the interactomics era (5 Feb, 2013)
  • Dirk Görlich – Transport through nuclear pores: the jelly path (Sep 9, 2013)
  • Lyndon Emsley – Surface enhanced NMR spectroscopy (Oct 3, 2013)
  • Fraydoon Rastinejad – Nuclear hormone receptors and metabolic pathways (Nov 22, 2013)

Seminars in 2012

  • Tim Cross – The Influence of Membrane Mimetic Environments on Membrane Protein Structures: M2 Protein and Others (27 Mar, 2012)
  • Wim Hol – Towards understanding the sophisticated two-membrane-spanning Type II Secretion System (13 Apr, 2012)
  • Imre Berger – Towards Eukaryotic Structural Complexomics (8 May, 2012)
  • Katie Henzler-Wildman – Conformational Exchange and the Mechanism of Multidrug Resistant Transport by EmrE (14 May, 2012)
  • Erik Zuiderweg – Non-canonical ligand-binding events as detected by NMR (22 May, 2012)
  • Changlin Tian – Structural Studies of Outer Membrane “Channel” proteins of Mycobactrium tuberculosis (16 Aug, 2012)
  • Debora Marks – Evolutionary co-variation from genomic sequencing reveals 3D protein structure and function (11 Sep, 2012)
  • Andrew Baldwin – Probing the structure, dynamics, and function of complex systems with NMR, ion mobility mass spectromety, electron microscopy and Rosetta: application to the human chaperone alphaB-crystallin (23 Nov, 2012)
  • Leonard Foster – Measuring the response of the interactome and phosphoproteome to bacterial infection (27 Nov, 2012)
  • Alfred Vertegaal – Cracking the SUMO signalling code (27 Nov, 2012)

Seminars in 2011

  • Liesbeth Veenhoff – Transport of membrane proteins through the nuclear pore complex requires long fl­exible linker (10 Feb, 2011)
  • Peter Tieleman – Watching lipids move: computer simulations of defects, flip-flop, and fusion (4 Apr, 2011)
  • Trevor Douglas – Viruses: Natural Supramolecular Architectures and Synthetic Building Blocks (8 Apr, 2011)
  • Henk Stunnenberg –  ‘systems biology’ to gain molecular insight into differentiation and transformation pathways (14 Apr, 2011)
  • Rob Russell – Predicting structure and mechanism in biological interaction networks (17 May, 2011)
  • Alain Milon – Structure and dynamics of membrane components (sterols, peptides and proteins) by liquid and solid state NMR (23 May, 2011)
  • Randy Read – Structures of a redox switch modulating blood pressure: angiotensinogen and renin (23 May, 2011)
  • Alan E. Mark – Atomistic models of biomolecular systems: The search for certainty in an uncertain world (15 Sep, 2011)
  • Ljiljana Pasa-Tolic – Towards Quantitative Intact Protein Mass Spectrometry (14 Oct, 2011)
  • Walter Chazin – Structural architecture and remodeling of modular multi-domain proteins in DNA processing machinery (19 Oct, 2011)
  • Anne S. Ulrich – Structure-function analysis of short antimicrobial peptides in membranes (7 Nov, 2011)
  • Tom Woolf – Molecular Dynamics Calculations of Conformational Changes in the Sarcoplasmic Reticulum Ca-ATPAse pump (SERCA) (1 Dec, 2011)
  • Vitali Tugarinov – Methyl-based NMR Evidence for Symmetry in Functionally or  Crystallographically Asymmetric Homodimers (12 Dec, 2011)

Seminars in 2010

  • Venki Ramakrishnan – What ribosome structures reveal about tRNA selection during decoding of mRNA (22 Jan, 2010)
  • Holger Stark – Ribosome dynamics and tRNA movement as visualized by time-resolved electron cryomicroscopy (5 Feb, 2010)
  • Peter Peters – Towards Visualization of Nanomachines in their Native Cellular Environment (12 Feb, 2010)
  • Sheena Radford – Molecular insights into protein self-assembly mechanisms in amyloid disease (26 Mar, 2010)
  • Martin Engelhard – Biophysics: Tools to answer biological questions in cellular signal transfer and Prion disease (16 Apr, 2010)
  • Maarten Merkx – Engineering protein switches for intracellular imaging and diagnostics (26 Apr, 2010)
  • Marloes Groot – Imaging the brain & Enzyme dynamics (31 May, 2010)
  • Beat Meier – Characterization of Fibrils and Prions by Solid-State NMR (29 June, 2010)
  • Ming Tan – Structural Basis of Norovirus-Host Interaction and Implications in Disease Control and Prevention (1 Oct, 2010)
  • Blake Wiedenheft – Biochemical and structural characterization of the CRISPR-cas immune system (RNAi-like) in prokaryotes (19 Oct, 2010)
  • Robert G. Griffin – MAS NMR Determination of the Structure of an Amyloid Fibril (26 Oct, 2010)

Seminars in 2008

  • Dino Moras – Nuclear Hormone Receptors: Structural basis for some functional features (8 Feb, 2008)
  • Patric Fuchs – Molecular insights into transmembrane peptides and surfactants dynamics from computer simulations (21 Feb, 2008)
  • Ariel Fernandez – Curbing drug side effects by exploiting integrative ideas in molecular biophysics (4 Mar, 2008)

Seminars in 2007

  • Hans Gerritsen – Non-linear excitation and spectroscopy in fluorescence microscopy (16 Feb, 2007)
  • Michael Zasloff – Antimicrobial peptides in human health and disease (8 Mar, 2007)
  • Dmitri Svergun – Analysis of Biomacromolecular Solutions with Small-Angle Scattering (1 Jun, 2007)
  • Thomas Kiefhaber – Fast Folding and Assembly of a Small Trimerization Domain from Phage T4 Fibritin (7 Dec, 2007)
  • Zihe Rao – Structural proteomics of the SARS coronavirus: structure, function and interaction of the replicase proteins (13 Dec, 2007)

Seminars in 2006

  • Gijs Wuite – A singular view of DNA transactions (31 Mar, 2006)
  • Petra Schwille – Probing the Local Micro-environment in Model and Cell Membranes on a Single Molecule Scale (12 May, 2006)
  • Jens Andersen – Organellar proteomics: turning inventories into insights. (29 Sep, 2006)
  • Steven O. Smith – Transmembrane Helix Interactions in Membrane Protein Structure, Function and Disease (20 Dec, 2006)

Seminars in 2005

  • Anthony Lee – Membranes: a game of two halves (16 Dec, 2005)
  • Geert-Jan Boons – Glycosidase inhibitors as novel cancer therapeutics (12 Oct, 2005)
  • Randy Hampton – Cellular Regulation by Protein Quality Control (27 Apr, 2005)

Seminars in 2004

  • Michael Sattler – NMR studies of molecular recognition and dynamics during spliceosome assembly and RNA interference (24 Sep, 2004)
  • Frank Sobott – Making elephants fly: Nano-ESI and tandem-MS for the characterisation of noncovalent protein complexes in the gas phase (24 Sep, 2004)
  • Colin Stirling – Co-ordination of Molecular Chaperones: many hands make light work! (2 Nov, 2004)
  • Catherine Etchebest – Escherichia coli mechanosensitive channel: Conformational changes and membrane environment (16 Dec, 2004)